重组小鼠巨噬细胞集落刺激因子

M-CSF 也称为 CSF-1，是一种四α螺旋束细胞因子，是巨噬细胞存活、增殖和分化的主要调节剂 。M-CSF 蛋白对于破骨细胞祖细胞的存活和增殖也至关重要。M-CSF 还可启动和增强巨噬细胞对肿瘤细胞和微生物的杀伤，调节巨噬细胞释放细胞因子和其他炎症调节剂，并刺激胞饮作用 。

(纯度) Purity

≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining).

(内毒素) Endotoxin

≤10 EU/mg by the LAL method.

(生物活性) Bioactivity

The activity is determined by the dose-dependent proliferation of murine NFS-60 cells is ＜ 0.05 ng/mL, corresponding to a specific activity of ≥ 2 E7 units/mg.

(种属) Species

Mouse

(表达系统) Expression System

CHO

(预测分子量大小) Mol. Weight

26 kDa (monomer)

(表达区间) Expression Region

Lys33-Glu262

(标签) Tag Info

Tag free

(剂型) Formulation

Lyophilized

(溶液) Buffer

Lyophilized from a 0.22 μm-filtered solution containing PBS, 5% Mannitol and 0.01% Tween 80, pH7.4.

(规格) Size：1mg

(复溶) Reconstitution

It is recommended to redissolve in sterile deionized water.

(运输) Shipping

The product is shipped with blue ice.

(存储) Storage & Stability

36 months at -20°C to -80°C in lyophilized state;

6 months at -20°C to -80°C under sterile conditions after reconstitution;

7-10 days at 2°C to 8°C under sterile conditions after reconstitution;

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.‌

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