重组人血清淀粉样蛋白A 蛋白质详细说明

SAA是一种急性相蛋白并与血浆高密度脂蛋白(HDL)结合。现在，研究把目光集中在炎性疾病急性反应期间的SAA类型。与已被充分证实的急性相蛋白-CRP比较，SAA被用来检验其在急性炎性疾病的诊断中是否有任何优点仍有待确定。

与CRP相仿，用以评估急性相反应进程。SAA是个灵敏的参数，它在炎性反应大约8h后开始升高，且超过参考范围上*早于CRP，然而CRP在正常人中的中位数值与参考范围上限的差距，大约有10倍。在SAA中仅有5倍。轻微感染，例如，许多病毒感染，SAA升高要比CRP更为常见。在感染性疾病中，SAA的上升要高于CRP，因此SAA测定，尤其对“正常”与微小急性相反应可提供更好的鉴别。通常约2/3感冒患者SAA升高，但少于1/2的患者相同表现CRP升高。在病毒感染病例中，SAA和CRP浓度升高见于腺病毒感染者。

分 子 量：14kDa
性    状：Liquid
浓    度：0.8mg/ml
产品来源：基因工程表达
分    类：重组蛋白
纯化方法：亲和层析
产品应用：Immunology research 
保存条件：Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
产品介绍：Serum amyloid A1 (SAA1) is a protein that in humans is encoded by the SAA1 gene. SAA1 is a major acute-phase protein mainly produced by hepatocytes in response to infection, tissue injury and malignancy. When released into blood circulation, SAA1 is present as an apolipoprotein associated with high-density lipoprotein (HDL). SAA1 is a major precursor of amyloid A (AA), the deposit of which leads to inflammatory amyloidosis.

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.